The burdens of brain atrophy

The World vs.MS

Brain health


In our previous article, understanding the brain in MS: introducing brain atrophy, we talked about brain atrophy – the loss of brain tissue and how it happens a little faster with MS. But let’s take a closer look at how brain atrophy impacts and disrupts the daily lives of people living with MS.

Brain atrophy has been linked to a range of different problems in MS, including physical disability1,2

Brain atrophy is a risk factor for fatigue7

Brain atrophy has been associated with cognitive impairment2

Brain atrophy has been linked to reduced emotional wellbeing11

Symptoms of brain atrophy can affect the relationships and daily lives of people living with MS and those around them:

References: 1. De Stefano N et al. J Neurol Neurosurg Psychiatry 2015; 0: 1-7. 2. Ferreira M. Cognitive deficits in multiple sclerosis. Arq Neuropsiquiatr 2010; 68(4): 632-641. 3. Giovanonni G et al. Brain health: A guide for people with MS. 2016. 4. Culpepper W et al. J Rehabil Res Dev 2015; 52(3): 263-272. 5. vs.MS global survey of people living with relapsing MS (RMS) and RMS care partners. 2015. 6. Sutliff M. Curr Med Res Opin 2010; 26(1): 109-119. 7. Tedeschi G et al. J Neuro Sci 2007; 263: 15-19. 8. Lerdal A et al. Eur J Neurol 2007; 14: 1338-1343. 9. Khan F. Front Neurol 2014; 15(5): 177. 10. Emotional and cognitive changes. Available at: Accessed: May 2017. 11. Mowry E et al. Neurology 2009; 72: 1760-1765. 12. Dealing with chronic illness and depression. Available at: Accessed: May 2017. 13. Benedict R et al. J Neurol Sci 2005; 231(1-2): 29-34. 14. Giovannoni G et al. Brain health: Time matters in MS. 2016.

Approval date: June 2017    GZEMEA.MS.17.05.0188

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